Both teams have done it tough of late, both will be hoping to replicate their superhero themed jerseys and lift a gear and entertain the crowd.
Jake Mamo has admitted Newcastle players are feeling guilty for the way former coach Rick Stone was dumped by the club on Monday.
Wests Tigers lock Martin Taupau and Broncos prop Adam Blair have both entered an early guilty plea, and will miss three and two weeks respectively.
The Newcastle Knights board have advised Rick Stone's position as head coach was 'untenable', with club legend Danny Buderus to act as interim coach.
Miraculously playing just one week after leaving the field with an irregular heartbeat, Newcastle centre Dane Gagai says his heart complications will reoccur.
Newcastle Knights took one step forward and several steps back as South Sydney ran riot on a night where Rabbitohs captain Greg Inglis and his team stood tall.
The Rabbitohs put on a clinic against a poor Knights side at ANZ Stadium on Saturday, with Greg Inglis and Dylan Walker scoring hat-tricks in a thrashing.
Newcastle's Queensland State of Origin speedster Dane Gagai will have more tests on his heart this week as he looks to play against South Sydney.
While he's only managed a handful of games since returning to the Knights, Clint Newton places great importance on his role in guiding the club's young stars.
South Sydney are looking to consolidate their place in the top four, Newcastle to avoid the wooden spoon, both teams need to win this clash at ANZ Stadium.