The Panthers will welcome back winger Dallin Watene-Zelezniak in Saturday's clash with the Roosters, but have lost back-rower Bryce Cartwright to injury.
Is it too early to say this Round 3 battle of east v west could be an early season preview of a Telstra Premiership finals match later on in September?
With plenty of key injuries and some high profile returns for Round 3 there is plenty to discuss in the NRL Fantasy Podcast.
Matt Elliott takes a look at three rising stars of the NRL Telstra Premiership - Manly's Brian Kelly, Cronulla's Jayden Brailey and Penrith's Viliame Kikau.
So much can change in a week in the Telstra Premiership, as Panthers captain Matt Moylan has quickly discovered in 2017.
How we rank the NRL's 16 clubs at the end of the second round of the 2017 Telstra Premiership season.
Quick starts, identical records and the incredible Queensland derby. The key numbers from Round 2 of the 2017 NRL Telstra Premiership.
Panthers rookie Dylan Edwards tasted his first win in the top grade and is keen for more opportunities as the season progresses.
The big blokes from another Cowboys-Broncos classic, Knights drought-breakers, Eels entertainers and Storm's two chief architects in the team of the week.
Scans have cleared Bryce Cartwright of serious injury after the Panthers forward was forced from the field during Sunday's win over Wests Tigers.