After Brett Stewart and Steve Matai were sidelined indefinitely, Sea Eagles coach Trent Barrett admitted the pair are no certainties to return next season.
While the Sharks and Bulldogs slipped up, the other finals contenders solidified their positions with a couple of weeks remaining before the business end.
Jamie Lyon has all but confirmed his NRL career is over with a hamstring injury set to keep him sidelined for Manly's final two matches.
The key talking points, injuries and judiciary news from the weekend's NRL Telstra Premiership action.
The Storm confirmed a top-two finish on a night where Cooper Cronk firmed as the Dally M favourite and Suliasi Vunivalu crossed for four tries.
Sea Eagles coach Trent Barrett believes Jamie Lyon might have played his final game, with the Manly skipper succumbing to a hamstring injury.
Melbourne winger Suliasi Vunivalu crossed for four first-half tries as his side overcame a resilient Manly outfit in a heated contest at Brookvale Oval.
Melbourne's hopes of featuring in the Holden Cup finals appear to be over following their draw with the bottom-placed Sea Eagles on Saturday afternoon.
The Sea Eagles and Storm have both confirmed their final 17 ahead of their Round 24 NRL Telstra Premiership clash at Brookvale Oval on Saturday night.
Jamie Lyon has just two games to play at Brookvale Oval before he retires, and his Sea Eagles teammates are set on sending their skipper out a winner.