Manly prop Brenton Lawrence is likely to be sidelined long-term due to back surgery in yet another injury blow for the club.
The Sea Eagles' depth is set to be tested over the coming weeks, the competition's in-form halfback, and can the Warriors put together a complete performance?
Five things we learnt from the Dragons win over the Sea Eagles in Round 4.
Manly halfback Daly Cherry-Evans has defended club doctor Thomas Gan's decision to pull him off for a concussion test late in their defeat to the Dragons.
A committed Dragons side have made it back-to-back wins after disposing of an out-of-sorts Manly outfit 12-4 in Wollongong on Saturday night.
Long-serving Manly hooker Matt Ballin has demonstrated impressive commitment by taking on a full-time university degree over the course of his NRL career.
Warringah Council and the Manly Warringah Sea Eagles are taking action to restore the condition of the Brookvale Oval playing surface.
Two sides defying the critics face off in the first Wollongong fixture for 2015, and the 100th NRL game at the historic venue.
It wasn't until last year's Four Nations when Toa Samoa forwards Jesse Sene-Lefao and Leeson Ah Mau discovered their shared history.
One of the shining lights for Manly in their past two games has been the sparkling form of back-rower Feleti Mateo filling in for the injured Kieran Foran.