The Rabbitohs are reeling from last week's loss to the Cowboys and the absence of their star half, and could be brought down again by an in-form Sharks side.
Sharks prop Andrew Fifita will miss just two weeks after his dangerous throw charge was downgraded at the NRL judiciary on Wednesday night.
Boom youngster Jack Bird has declared he is loving every minute in first grade, having exploded out of the blocks in the first three games of his NRL career.
After starting the competition as the only undefeated team, the Knights have lost two on the trot, while the Sharks have undergone a resurgence.
The Sharks have claimed their first win at home in almost a year, defeating the Knights 22-6 in dreary conditions at Remondis Stadium on Friday night.
A Sharks side fresh from their first win of the season take on a Knights outfit reeling from their first loss, in what could be a turning point for both teams.
Sharks coach Shane Flanagan has encouraged fans to take advantage of the club’s ticketing arrangement with Sydney Trains for Friday's clash with Newcastle.
Andrew Fifita may be conceding an error and a penalty per game this season but he is still content with his rise back to form after his disrupted pre-season.
Penrith's record-breaking workhorse, a veteran steals the show, and the rise of the Red V Wall. These are the key numbers and statistics that defined Round 5.
Trent Hodkinson's golden boot, the rise of the Red V Wall, restarts cause havoc and Manly unearth a future superstar.