The Titans took one massive step towards their first finals campaign in six seasons, with their big men up front causing all the damage in their 20-point win.
Parramatta players are preparing to face the full force of former teammate Junior Paulo for the first time after the big front-rower's mid-season switch.
The Storm confirmed a top-two finish on a night where Cooper Cronk firmed as the Dally M favourite and Suliasi Vunivalu crossed for four tries.
Sea Eagles coach Trent Barrett believes Jamie Lyon might have played his final game, with the Manly skipper succumbing to a hamstring injury.
North Queensland have snapped a three-game losing run, bouncing back to get the better of the Warriors at 1300SMILES Stadium on Saturday night.
Titans playmaker Tyrone Roberts overcame a knee injury – and nerves – to lead his side to victory over the side he departed at the end of last season.
The efforts of retiring workhorse Jeremy Smith has helped Danny Levi push through the pain barrier and delay back surgery the entire 2016 campaign.
Melbourne winger Suliasi Vunivalu crossed for four first-half tries as his side overcame a resilient Manly outfit in a heated contest at Brookvale Oval.
The Cowboys and Warriors have both confirmed their final 17 ahead of their Round 24 NRL Telstra Premiership clash at 1300SMILES Stadium on Saturday night.
Melbourne's hopes of featuring in the Holden Cup finals appear to be over following their draw with the bottom-placed Sea Eagles on Saturday afternoon.