Two decades ago these sides met for the Warriors' first-ever competitive match. Now, on the back of good wins for both sides, they meet again at a crucial time.
This game represents short-term salvation to two teams who have just three wins in their past 18 matches between them.
Can anything stop the South Sydney juggernaut, it depends which Parramatta side turns up.
The Newcastle Knights are somehow undefeated after three weeks but face their toughest test in a while against a Panthers side with lofty goals this season.
The Concord Kids take on the Belmore Bruisers in what is sure to be an epic clash at ANZ Stadium.
The Roosters have scored a solid 20-12 victory over fellow premiership contenders the Penrith Panthers at Allianz Stadium on Monday night.
A try in the final four minutes to Knights back-rower Jeremy Smith has seen Newcastle extend their unbeaten start to the season to three wins.
South Sydney have continued their unbeaten start to their premiership defence with a rugged 20-6 victory over the Wests Tigers.
Titans fullback Josh Hoffman has praised the manner in which his cousin Dane Gagai has rejoined the Origin conversation.
Two late tries made the result respectable but in truth the Sharks had no answer for Melbourne who romped to victory in front of 13,015 fans at AAMI Park.