The Storm handed the Roosters their biggest loss of the season six weeks ago, but an improving Tricolours outfit should pose more of a problem on Saturday.
As the Titans begin to build towards a finals appearance that was perhaps unlikely at the start of 2016, the Eels will be hoping to keep their chances alive.
The Knights came within four of stunning Melbourne last week, but are they capable of ending Cronulla's incredible winning streak?
Two of the NRL's most exciting teams are also in form, with the Raiders enjoying a three-game winning streak and the Warriors having won four of their last six.
Two sides who won in Round 19 clash on Friday night, with Brisbane hoping to stay in touch with the top four and Penrith needing to hang with the top eight.
Two monstrous forward packs go head-to-head in what looms as a crucial battle in the race for the top four.
The Cronulla Sharks have made it 14 wins in a row with a hard fought victory over the Roosters at Allianz Stadium on Monday night.
The Panthers have launched an impressive second half comeback to beat the Eels in an absolute thriller on Sunday afternoon at Pepper Stadium.
The Storm have beaten a spirited Knights outfit who pushed them for the entire 80 minutes and threatened to steal the game at the death.
The Brisbane Broncos have snapped a two-game losing streak with a resounding win over the South Sydney Rabbitohs at ANZ Stadium on Saturday night.