Fresh off the bye, the Sharks will be searching for their 11th consecutive victory over a Warriors side who head across the Tasman on a three-game winning run.
Newcastle get some much needed troops back, but will it be enough to upset the Dragons on Saturday afternoon?
Andrew Voss predicts the Maroons will win Game Two and looks at Manly's woes, Radradra, the Titans' form and the importance of a huge Round 16.
Fresh off a bye and a last-start win over Manly, Penrith return home to face a South Sydney side desperate to win for the first time since Round 11.
The Titans continued their impressive 2016 season with a controlled performance against Manly, earning a comfortable 30-10 win at Cbus Super Stadium.
Despite a late surge from the Roosters, the Warriors have held firm to clinch a crucial victory in a low-scoring affair at Mt Smart Stadium on Sunday night.
The St George Illawarra Dragons have beaten the Melbourne Storm and knocked them off the top of the NRL Telstra Premiership ladder.
John Sutton's return wasn't enough to inspire the Rabbitohs to victory against Parramatta on Friday night, with the Eels prevailing 30-12 at ANZ Stadium.
Two teams who let two competition points slip through their fingers last week meet on a mid-winter Monday night desperate to keep their finals flame flickering.
The mid-season revival in Auckland is well and truly gaining velocity, and the Warriors take on a Roosters side down on luck and form.