The Canterbury-Bankstown side has been a significant Achilles heel for Craig Bellamy's men over the years and have won the past four meetings.
The premiership favourites are starting to make their move, while the Gold Coast Titans are desperately holding onto top eight hopes.
The Cowboys might be heavy favourites to extend their winning run to 12, but the absense of Johnathan Thurston won't help their chances against the Sharks.
Two of the NRL Telstra Premiership's most entertaining sides meet this weekend, with the winner almost assured a spot inside the top eight.
The Broncos will be looking to prove that their herculean defensive effort against the Storm was no fluke when they tackle a desperate Knights side this week.
This time last year Manly were the NRL's outright leaders; now they're running last. But recent form suggests the Sea Eagles could spring a surprise here.
The Sydney Roosters have prevailed over the St George Illawarra Dragons in an exciting Monday night encounter at Allianz Stadium.
A defensive performance for the ages has seen Brisbane snap an eight game losing streak against the Storm to record a brave win at AAMI Park.
The Cronulla Sharks have held on to beat the Newcastle Knights in a high scoring contest at Hunter Stadium.
A complete Warriors performance, encouraging signs for Titans new recruits, mini Manu makes his mark and Henry hits back at recruitment speculation.