Despite a frenetic final few minutes, the Bulldogs have done enough to defeat the Roosters in a highly entertaining contest at Allianz Stadium.
South Sydney enjoy a good record in Cairns but won't necessarily have the local crowd on their side against the reigning champions.
It's officially do or die time on Manly's struggling season as they head home to Brookvale after a tough two-week road trip through Queensland.
It will be a "Winter Wonderland" theme at GIO Stadium on Sunday afternoon and it won't get much colder for the Knights if they're to fall to the Raiders.
The western Sydney derby features two sides capable of playing some of the most attractive football in the Telstra Premiership.
Two top eight contenders clash on Saturday afternoon as the Titans travel to Auckland to face the Warriors in what will be Simon Mannering's 250th NRL game.
It's been six weeks since either of these two teams tasted defeat – easily the longest such run of any game this weekend and it promises to be a classic.
Queensland heroes Cameron Smith and Cooper Cronk return to Suncorp Stadium to face the Broncos with the Storm boasting an impressive record at the venue.
With 10 weeks to go until the start of the finals, the equation is simple for the Roosters; win nine matches or they can start preparing for 2017.
Despite trailing with less than 20 minutes remaining, the Cowboys have finished strongly to get the better of a spirited Sea Eagles side at 1300SMILES Stadium.