A field goal from Titans recruit Jarryd Hayne with barely seconds remaining has handed Gold Coast a crucial win over Wests Tigers at Campbelltown Stadium.
Anthony Milford and Ben Hunt rediscovered their form as the Broncos put the Eels to the sword on Friday night at Suncorp Stadium.
A Josh Reynolds try in the second half of golden point extra time has handed the Bulldogs a dramatic four-point win over the Sea Eagles at ANZ Stadium.
All eyes will be on GIO Stadium on Monday night as two of the form teams of the competition go head-to-head.
The Cowboys are desperate to rediscover winning form ahead of the finals while the Roosters are just keen to end their season on a high.
Led by skipper Matt Moylan, representative back-rower Trent Merrin and champion hooker Peter Wallace, the Panthers are pressing for a finals berth.
Both teams will take plenty of motivation into this one, with the Warriors well in the finals race and Souths out to snap a nine-game losing streak.
The Tigers and Titans head into their Round 23 showdown having exceeded all expectations, but both now face a big challenge to make the top eight.
The Sharks' unbeaten run is over but they're expected to bounce back against a Dragons side that welcomes back star fullback Josh Dugan this week.
These sides last met in the season-opener at Pirtek Stadium, and have both faced their separate challenges ahead of their meeting on Friday night in Brisbane.