A dominant second half has seen the Panthers keep their finals hopes alive, running in seven tries to down the Knights at Hunter Stadium on Sunday afternoon.
A powerful display from St George Illawarra has seen the Red V run in five tries to hand Cronulla their second straight loss at UOW Jubilee Oval on Saturday.
The Rabbitohs have claimed their first win since Round 11, denting the Warriors' finals hopes in the process at Mt Smart Stadium on Saturday night.
A field goal from Titans recruit Jarryd Hayne with barely seconds remaining has handed Gold Coast a crucial win over Wests Tigers at Campbelltown Stadium.
Anthony Milford and Ben Hunt rediscovered their form as the Broncos put the Eels to the sword on Friday night at Suncorp Stadium.
A Josh Reynolds try in the second half of golden point extra time has handed the Bulldogs a dramatic four-point win over the Sea Eagles at ANZ Stadium.
All eyes will be on GIO Stadium on Monday night as two of the form teams of the competition go head-to-head.
The Cowboys are desperate to rediscover winning form ahead of the finals while the Roosters are just keen to end their season on a high.
Led by skipper Matt Moylan, representative back-rower Trent Merrin and champion hooker Peter Wallace, the Panthers are pressing for a finals berth.
Both teams will take plenty of motivation into this one, with the Warriors well in the finals race and Souths out to snap a nine-game losing streak.