Beau Scott (Parramatta Eels), Konrad Hurrell (Warriors), Ryan Hoffman (Warriors) and Matthew Wright (North Queensland Cowboys) have been added to the World All Stars squad ahead of Saturday night's Harvey Norman Rugby League All Stars at Suncorp Stadium.
They will replace Paul Gallen, Antonio Winterstein, Simon Mannering and Roger Tuivasa-Sheck, who have been forced to withdraw from the match.
Gallen said he was disappointed to be missing the All Stars game due to a calf injury.
"I'm really disappointed that I won't be playing," Gallen said.
"I wanted to give myself every chance, which is why I made the decision today, but I haven't been able to train over the past two weeks after aggravating a calf injury.
"To go into the first game of the year, and such an intense and important game, with a couple of ball work sessions under my belt would have been too risky."
The World All Stars squad is now as follows:
1 Jordan Kahu (Broncos)
2 Semi Radradra (Eels)
3 Jarrod Croker (Raiders)
4 Josh Morris (Bulldogs)
5 Nene Macdonald (Titans)
6 Gareth Widdop (Dragons)
7 Adam Reynolds (Rabbitohs)
8 James Graham (Bulldogs)
9 Cameron Smith (c, Storm)
10 Tom Burgess (Rabbitohs)
11 Chris Lawrence (Tigers)
12 Ryan Hoffman (Warriors)
13 Jeremy Smith (Knights)
14 Michael Ennis (Sharks)
15 Kane Evans (Roosters)
16 Konrad Hurrell (Warriors)
17 Trent Merrin (Panthers)
18 Beau Scott (Eels)
19 Martin Taupau (Sea Eagles)
20 Matthew Wright (Cowboys)