It will be a Prime Minister's XIII clash of extra significance on Friday night with Australian Prime Minster Scott Morrison set to fly into Suva for the clash at ANZ National Stadium.

Morrison will become the first Australian leader to attend the fixture since its inception in 2005, which has previously been held in Papua New Guinea up until this season under a new agreement with the Fijian Government and Fiji Rugby League.

Morrison joined Kangaroos coach Mal Meninga and Jillaroos coach Brad Donald in Canberra last month to help select squads for the annual men's and women's clashes.

The avid Cronulla Sharks supporter is set to spend time with Fijian Prime Minister Frank Bainimarama during the trip following the recent Vuvale Partnership agreement between the two nations.

"The diplomacy between the two nations is really important and we understand how Fiji is a really important neighbour to Australia," Meninga told NRL.com.

"It's great we've got a Prime Minister at the moment that loves rugby league and places great importance on security around surrounding nations near Australia.

"We're looking forward to our Prime Minister coming here tomorrow and hopefully be a part of the team, maybe a pre-game prep talk to the players, we'll see what happens.

"Above all it's nice to have someone so invested in this program."

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Meninga reiterated the Prime Minister's XIII side's mission on tour was to help deliver key messages around preventing violence against women and children.

"That is the most important part of the trip and having the women here is great," Meninga said.

"It's very important from a social point of view how lucky we are as rugby league people to spread the message in this country.

"Saying no to violence against women and children is an easy message for us to believe in it.

"Every time we talk about it it's with real conviction. Real men don't harm women and children but rather keep them safe."