The Eels are one of two teams to win all three games, but the high-flying Sea Eagles loom as their biggest test yet.
Parramatta motored past the Broncos last week to protect their spot atop the ladder, while Manly punished the Bulldogs with a sizzling performance from fullback Tom Trbojevic.
These two traditional rivals will leave nothing in the tank at Bankwest Stadium.
Eels: Oregon Kaufusi replaces Ray Stone on the bench in Parramatta's only change, with George Jennings and David Gower were omitted from the 19-man squad on game day and Will Smith dropping out of the squad 24 hours before kick-off. The Eels have won eight of their past 10 games against Manly. Ray Stone and Will Smith were cut from the squad 24 hours before kick-off.
Sea Eagles: Manly are 1-17 with Jack Gosiewksi and Tevita Funa dropping off the extended bench. Morgan Boyle and Brendan Elliott were omitted from the 21-man squad on Friday night. Winger Jorge Taufua has scored eight tries in 12 games against the Eels.
The credit was shared among his teammates, but Eels fullback Clint Gutherson had a blinder against the Broncos as he seemed to pop up everywhere. He is pitted against Tom Trbojevic, who dominated the Bulldogs with a two-try performance last Sunday. It's set to be an enthralling No.1 battle.