Penrith lost playmaking lock Isaah Yeo just nine minutes into their Suncorp Stadium clash with Brisbane on Saturday night after he was felled while trying to score.
Yeo, who failed his HIA activating 18th man Jaeman Salmon, appeared to be out before he hit the ground and Broncos prop Thomas Flegler was subsequently sin-binned for the high shot.
A double blow for Wests Tigers at Suncorp Stadium on Saturday with Luke Garner (ankle) and Alex Seyfarth (knee) both forced from the field during the first half.
Manly lost bench utility Dylan Walker (head knock) late in the contest when he came off second best trying to tackle Wests Tigers big man Stefano Utoikamanu running the ball back from the kick-off.
The Warriors lost three players their round 19 clash against Souths Sydney, with Jack Murchie and Eliesa Katoa both suffering head knocks and failing HIAs in the first half. The team also lost star prop Addin Fonua-Blake to a finger injury in the second half.
Casualty Ward By Club
The Roosters suffered a double blow at Sunshine Coast Stadium on Friday night with outside backs Matt Ikuvalu and Billy Smith both suffering ankle injuries.
Smith played just 16 minutes before he was forced from the field and he returned to the sideline in a moon boot.
Ikuvalu had to be helped from the field in the 34th minute after his left leg was twisted awkwardly in a tackle by Knights winger Dom Young.
The Raiders lost star prop Josh Papalii to a failed HIA following a head knock in the first half of Thursday night's clash with Parramatta.
Meanwhile, Parramatta's Marata Niukore left the field after suffering a suspected knee injury in a 30th-minute tackle.
Cowboys fullback Hamiso Tabuai-Fidow may have played his last game of the season after undergoing an emergency appendectomy on Wednesday.
Tabuai-Fidow was due to line up for the Cowboys against the Storm on Friday night but now faces up to six weeks on the sidelines.
It's a cruel blow for the Cowboys speedster who made a statement at fullback with a try and 271 metres against the Roosters last week.
The Cowboys are yet to confirm a replacement for the 19-year-old, who will remain in hospital for another 24 hours following surgery.
Storm winger George Jennings will miss 4-6 weeks with a knee injury suffered during the side's win against Newcastle.
Jennings did damage to his posterior cruciate ligament but will aim to return before the finals.
Harris, Bowen suffer season-ending knee injuries
The competition leaders will also be without Origin stars Cameron Munster, Dale Finucane and Felise Kaufusi with the trio rested.
On the Gold Coast, the Titans will be without key trio Jamal Fogarty, Phil Sami and Erin Clark for Sunday's clash against the Dragons due to injuries.
Fogarty has been cleared of a thumb fracture after leaving the field in last week's loss to the Eels but won't be risked this week for fear of potential infection.
Brown confirms long-term injuries to Harris and Egan
Sami faces 3-4 weeks on the sidelines with an ankle injury while Clark (elbow) should only miss a week.
At Manly, scans have cleared Karl Lawton of a back fracture but he'll miss this week's clash and aim for a return in round 20, while the Dragons will be without Brayden Wiliame (groin) for their clash with the Titans.
Cronulla are hopeful Matt Moylan (calf) will be available for their round 20 clash against the Sea Eagles.
To view the complete NRL Casualty Ward, please visit the hub page.
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