A Penrith side that is still to suffer a loss in 2021 welcomes a Canterbury side with a 1-10 record.
The Panthers - fresh off a 56-12 thrashing of South Sydney - are arguably in better form now than when they scored a 28-0 win over the Bulldogs in round two.
Anything less than Canterbury's best means a win is highly unlikely. But if they can start well and generate some self-belief they just might be able to make something happen as the game approaches the final whistle.
After conceding 30 points in a loss to Gold Coast last weekend a stronger defensive line would be a great start.
Match: Panthers v Bulldogs
Round 12 -
Venue: BlueBet Stadium, Penrith
Panthers: Maroons back-rower Kurt Capewell (crusher) accepted a one-week ban with an early plea, allowing Moses Leota (shoulder) to slot back in after his late withdrawal last week. Liam Martin shifts back to the second row.
Dylan Edwards (hamstring) has failed to recover so Stephen Crichton stays at fullback and Paul Momirovski partners hat-trick hero Matt Burton in the centres.
Izack Tago is the 18th man, with Robert Jennings dropping off the extended bench on game day. Mitch Kenny and Lindsay Smith were omitted when the squad was trimmed to 19 players 24 hours out from kick-off.
The Panthers have won their past 14 games at BlueBet Stadium.
Bulldogs: In a late change, Brad Deitz starts at hooker with Jackson Topine moving to the bench.
Jack Hetherington returns at prop and captain Josh Jackson is back locking the scrum in a major revamp of the Canterbury pack.
Ava Seumanufagai drops back to the interchange, Adam Elliott moves from No.13 to the second row in place of Chris Smith (suspended) and Topine returns from injury to replace Sione Katoa (suspended) in the squad..
Fullback Dallin Watene-Zelezniak will play despite suffering a foot injury in the loss to Gold Coast and rookie centre Aaron Schoupp retains his place.
Corey Waddell is the 18th man with Tui Katoa omitted from the reserves an hour before kick-off. Kyle Flanagan and Renouf Atoni were dropped from the bench on Friday.
Bulldogs winger Nick Meaney has scored tries in his past three games.
Fullback for Panthers is number 1 Stephen CrichtonFullback for Bulldogs is number 1 Dallin Watene-Zelezniak
Winger for Panthers is number 2 Charlie StainesWinger for Bulldogs is number 2 Nick Cotric
Centre for Panthers is number 3 Paul MomirovskiCentre for Bulldogs is number 3 Will Hopoate
Centre for Panthers is number 4 Matt BurtonCentre for Bulldogs is number 4 Aaron Schoupp
Winger for Panthers is number 5 Brian To'oWinger for Bulldogs is number 5 Nick Meaney
Five-Eighth for Panthers is number 6 Jarome LuaiFive-Eighth for Bulldogs is number 6 Brandon Wakeham
Halfback for Panthers is number 7 Nathan ClearyHalfback for Bulldogs is number 7 Jake Averillo
Prop for Panthers is number 8 Moses LeotaProp for Bulldogs is number 8 Jack Hetherington
Hooker for Panthers is number 9 Apisai KoroisauHooker for Bulldogs is number 14 Bradley Deitz
Prop for Panthers is number 10 James Fisher-HarrisProp for Bulldogs is number 10 Luke Thompson
2nd Row for Panthers is number 11 Viliame Kikau2nd Row for Bulldogs is number 11 Adam Elliott
2nd Row for Panthers is number 12 Liam Martin2nd Row for Bulldogs is number 12 Matt Doorey
Lock for Panthers is number 13 Isaah YeoLock for Bulldogs is number 13 Josh Jackson
Interchange for Panthers is number 14 Tyrone MayInterchange for Bulldogs is number 9 Jackson Topine
Interchange for Panthers is number 15 Scott SorensenInterchange for Bulldogs is number 15 Joe Stimson
Interchange for Panthers is number 16 Matthew EisenhuthInterchange for Bulldogs is number 16 Dylan Napa
Interchange for Panthers is number 17 Spencer LeniuInterchange for Bulldogs is number 17 Ava Seumanufagai
Reserve for Panthers is number 21 Izack TagoReserve for Bulldogs is number 20 Corey Waddell
- Referee: Matt Noyen
- Touch Judge: Jon Stone
- Touch Judge: Mark Bohan
- Senior Review Official: Alan Shortall
James Fisher-Harris v Luke Thompson: Penrith's unsung hero faces another stern test in the shape of the aggressive Englishman. Thompson has been a shining light for the Dogs pack in the matches he's played. He needs to lead the way once again for his side to be any hope.
When the two teams met in Round 2, the Bulldogs had just 41 per cent of possession and made one line break over the 80 minutes. Canterbury didn't have one forward that ran for more than 100m in the match.
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