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Roosters halfback Sam Walker.

The Sydney Roosters have moved their round 16 clash with Melbourne to Newcastle's McDonald Jones Stadium following the latest COVID-19 outbreak in Sydney.

The Thursday night game on July 1 has been shifted as a precautionary measure.

Penrith announced on Friday that they would be refunding tickets purchased for next Friday's showdown with Parramatta.

The Panthers said a reduced ticket allocation would be made exclusively available to 2021 members via a redemption process.

Three Canterbury players have been instructed by NSW Health to immediately undergo a COVID-19 test and self-isolate after attending an exposure site.

The NRL was advised late on Thursday night that prop Dylan Napa, halfback Brandon Wakeham and centre Aaron Schoupp attended The Royal Hotel in Bondi last Sunday, which was attended by a person who has tested positive to COVID-19.

The NRL and clubs are due to hold a phone hook-up on Friday afternoon to discuss a range of measures that will need to be taken for next week's round.

NSW Premier Gladys Berejiklian said on Friday morning announced anyone who lives or has worked in four Eastern Sydney local government areas over the past 14 days - Woollahra, Waverley, Randwick and the City of Sydney - would only be allowed to leave home to travel for necessary work or education, participate in outdoor exercise, to care for a relative or buying essential goods or services.

The order is due to begin at 11.59pm AEST on Friday, running until 11.59pm next Friday.

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The NRL issued a clear directive to all Sydney-based clubs on June 17 that players and staff were not to attend any restaurants, clubs or bars in the Waverley Local Government area.

All clubs in the Greater Sydney, Wollongong and Central Coast areas were placed on level-three biosecurity protocols from Tuesday evening and are not permitted to leave home except to train or access essential services.

Canterbury's squad will not train until the test results of the three players are known. The players have not been in contact with representatives from any other club nor does it impact any State of Origin player.

Roosters coach Trent Robinson said "the people of the Hunter region love rugby league so it was an easy call to take our round 16 home game to Newcastle.

"We always enjoy making the trip to Newcastle and playing at McDonald Jones Stadium, so we're really looking forward to hosting this game at the ground for all the passionate rugby league fans of Newcastle, including our Roosters Members and supporters from the region who will benefit from this being a true home game for them."

The club said Roosters members would be provided with ticketing information in the next few days.

The Roosters are set to welcome back halfback Sam Walker (shoulder) and forward Sitili Tupouniua (foot) in the match, while Jesse Bromwich (elbow) is likely to return for the Storm.