The Raiders travel to Penrith's BlueBet Stadium looking to end the Panthers' incredible 20-game winning streak on home turf, a record that stretches back to 2019.
The Panthers' winning streak eclipses Manly's efforts, who won 19 straight games at their home ground between from 1967, the same year the western Sydney club entered the competition.
Ironically, it was the Raiders who last handed defeat to the Panthers at the foot of the mountains during their run to the 2019 grand final.
Since then the Panthers have won the last two, in particular the spicy showdown in April last year which landed Stephen Crichton with a contrary conduct charge for starting a melee involving Joseph Tapine.
There's been plenty of rivalry between the two sides before that with tense and last-minute finishes ensuring there's no love lost between the two clubs.
The Raiders are reeling after going down to the Cowboys in Canberra last week for a 2-4 start to the year while the Panthers are flying high with six wins on the board.
Sportsbet Betting preview: Panthers v Raiders
Panthers: Ivan Cleary has named an unchanged line-up to the side that beat the Broncos last week. Nathan Cleary was charged for a grade one dangerous contact tackle on Billy Walters but is free to play after escaping with a fine. Dylan Edwards was given an early breather in last week's win and will play.
No changes to the squad in Saturday's 24-hour update.
Raiders: The Raiders will be without skipper Elliott Whitehead after he suffered a deep cut to his mouth in a training collision with Ata Moriata during the week. Whitehead suffered damage to his upper gum and teeth and will need at least a week to recover. His place is taken by Hudson Young in the second row.
A couple of backline changes with Jordan Rapana replacing fullback Charnze Nicoll-Klokstad who moves to the bench and Xavier Savage coming onto the wing. Harry Rushton is in line for an NRL debut after being included on the bench with Emre Guler dropping out.
Fullback for Panthers is number 1 Dylan EdwardsFullback for Raiders is number 1 Jordan Rapana
Winger for Panthers is number 2 Charlie StainesWinger for Raiders is number 2 Nick Cotric
Centre for Panthers is number 3 Izack TagoCentre for Raiders is number 3 Matthew Timoko
Centre for Panthers is number 4 Stephen CrichtonCentre for Raiders is number 4 Semi Valemei
Winger for Panthers is number 5 Taylan MayWinger for Raiders is number 5 Xavier Savage
Five-Eighth for Panthers is number 6 Jarome LuaiFive-Eighth for Raiders is number 6 Jack Wighton
Halfback for Panthers is number 7 Nathan ClearyHalfback for Raiders is number 7 Brad Schneider
Prop for Panthers is number 8 Matthew EisenhuthProp for Raiders is number 8 Josh Papalii
Hooker for Panthers is number 9 Apisai KoroisauHooker for Raiders is number 9 Tom Starling
Prop for Panthers is number 10 James Fisher-HarrisProp for Raiders is number 10 Joseph Tapine
2nd Row for Panthers is number 11 Viliame Kikau2nd Row for Raiders is number 11 Corey Harawira-Naera
2nd Row for Panthers is number 12 Liam Martin2nd Row for Raiders is number 18 Hudson Young
Lock for Panthers is number 13 Isaah YeoLock for Raiders is number 16 Adam Elliott
Interchange for Panthers is number 15 Scott SorensenInterchange for Raiders is number 13 Ryan Sutton
Interchange for Panthers is number 16 Spencer LeniuInterchange for Raiders is number 14 Charnze Nicoll-Klokstad
Interchange for Panthers is number 17 Jaeman SalmonInterchange for Raiders is number 15 Harry Rushton
Interchange for Panthers is number 22 Soni LukeInterchange for Raiders is number 17 Corey Horsburgh
Replacement for Panthers is number 18 Robert JenningsReplacement for Raiders is number 19 Matt Frawley
- Referee: Grant Atkins
- Touch Judge: Drew Oultram
- Touch Judge: Kasey Badger
- Senior Review Official: Chris Butler
Jarome Luai v Jack Wighton: Teammates at Origin last year, both playmakers are in charge of their respective left edges and bring the creative flare to their sides. Luai has started the season with two tries and five try assists while Wighton has set up one and scored two himself. The pair's short side kicking games are where they're often relieving their halves partners so look for more of the same on Sunday.
The Panthers are leading the competition in key basic areas with an 82% completion rate average earning them at least 55% possession per game. They're firing in the yardage with 11,093 metres, more than 700 more than next best Parramatta. On the other side of the ledger, the Raiders lead the competition in one of the worst areas - handling errors (68) - and won't be able to afford a poor completion rate on Sunday.
Match: Panthers v Raiders
Round 7 -
Venue: BlueBet Stadium, Penrith