A virus resulted in Bulldogs winger Corey Allan being a late withdrawal from the side that played the Warriors on Sunday.
Casualty Ward By Club
After Allan said he was feeling unwell, club medical staff examined him before ruling him out.
Knights coach Adam O'Brien has confirmed powerful centre Bradman Best will play against the Sharks on Sunday after overcoming a minor collarbone injury.
Round 22 Late Mail
Sharks v Knights, Sunday 4.05pm at Moreton Daily Stadium, Redcliffe
Sharks: Josh Hannay's team will start 1-17 with Kai O'Donnell the 18th man.
Will Chambers was dropped in reaction to last week's loss to the Warriors.
Mawene Hiroti (hand) is close to a return but won't break into the side's backline this week with Siosifa Talakai in the centres.
Chambers and Hiroti were omitted from the reserves list 24 hours before kick-off.
The Sharks have won only two from seven at Queensland venues this season.
Knights: Newcastle will start 1-17 with Josh King the 18th man.
Hymel Hunt failed a head injury assessment last week but has been cleared to return.
Bradman Best (collarbone) has been cleared of any damage and is expected to play.
Connor Watson will start at lock in his 100th NRL game.
Jirah Momoisea and Star To'a dropped off the extended bench on Saturday.
The Knights have won their past three games against the Sharks.