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It's the final week of the NRL Fantasy season for 2021, and with several teams resting big names it's a doozy of a round for those chasing the overall prizes or playing head-to-head grand finals.

With one round to go, Shane E's team NRLFL Mighty Sea Eagles holds a 118-point lead over Kerry B's second-placed Brimstar at the top of the overall NRL Fantasy leaderboard.

While most head-to-head leagues wrapped up last week, those leagues still in action have a tricky grand final coming up with several strong clubs resting up star players ahead of the NRL finals.

Raiders: With Bailey Simonsson (groin) out, Charnze Nicoll-Klokstad is back in the No.1 jersey with Jordan Rapana shifting to his usual wing role. Joe Tapine is named despite concerns over knee and ankle problems while Sia Soliola starts at lock with Ryan Sutton shifting to the bench.

Hudson Young (75) has been in great scoring touch lately and is a genuine point of difference option, in just 2.5% of teams.

Roosters: Joey Manu (cheekbone), Fletcher Baker (suspension) and Ben Thomas (head knock) are out but Angus Crichton and Jared Waerea-Hargreaves return in the starting pack. Josh Morris and Adam Keighran also return in the centres, Matt Ikuvalu replaces Brad Abbey on the wing, Lachlan Lam switches to halfback, and Sam Walker and Egan Butcher go to the bench.

Sam Verrills (68) is coming off his season-best score while James Tedesco (9) had his worst, but should be expected to bounce back here.

Sharks: Matt Moylan starts at five-eighth and Teig Wilton in the second row with Luke Metcalf and Siosifa Talakai going to the bench.

Jesse Ramien (57) and Braydon Trindall (49) have been very solid in the latter part of the season.

Storm: Melbourne can lock up the minor premiership with a win here so have resisted the temptation to rest all their stars. Cameron Munster, Josh Addo-Carr (hamstring) and Jesse Bromwich (suspended) are the big outs, along with Reimis Smith, Christian Welch, Felise Kaufusi and Kenny Bromwich.

Nicho Hynes starts at five-eighth while the return of Dale Finucane means Brandon Smith moves to hooker with Harry Grant back to the bench. George Jennings and Dean Ieremia are on the wings, Marion Seve is at centre and Tui Kamikamica, Nelson Asofa-Solomona, Aaron Pene, Chris Smith and Finucane join the starting pack.

Eels: Junior Paulo has copped a one-match ban while Mitch Moses, Isaiah Papali'i, Dylan Brown and Clint Gutherson are among the players sitting this one out.

Hayze Perham is at fullback, Tom Opacic and Michael Oldfield are in the centres and Jake Arthur and Will Smith are the halves. Oregon Kaufusi, Bryce Cartwright, Keegan Hipgrave and Ray Stone are in the starting pack with Sam Loizou, Ky Rodwell, Shaun Lane and Sean Russell making up the bench.

Panthers: With the minor premiership up for grabs Penrith have named a full-strength team. Viliame Kikau is named to start after coming off the bench last week with Liam Martin in jersey 17. Spencer Leniu could return from an ankle injury via the reserves.

Nathan Cleary "only" scored 59 last week but remains the safest captaincy option around.

Broncos: With Tom Flegler and Brendan Piakura suspended, Ethan Bullemor starts at prop, Jordan Riki returns in the second row and TC Robati goes to the bench alongside Cory Paix and David Mead.

Anthony Milford (74) is racking up plenty of Fantasy points in his last few games as a Bronco and Payne Haas (69) remains a solid captaincy candidate. Albert Kelly (54) is very cheap if you're in the market for a cut-price option at $456k.

Knights: Jayden Brailey, Mitch Barnett and Hymel Hunt are out but Kalyn Ponga and the rest of the team's big names remain in a fairly strong round 25 line-up.

Star To'a replaces Hunt on the wing while David Klemmer and Brodie Joins join the starting pack and Chris Randall is at hooker. Phoenix Crossland and Jack Johns join the bench.

Mitchell Pearce (74) and Kalyn Ponga (65) were both standouts in last week's win, with Tyson Frizell (58) also strong.

Cowboys: Reuben Cotter (shoulder) is out, Jason Taumalolo switches to lock and Coen Hess returns at prop. Taumalolo scored 48 points in 61 minutes last week and looks set to finish the season with an underwhelming sub-50 average.

Sea Eagles: Sean Keppie and Taniela Paseka replace Toafofoa Sipley and Curtis Sironen on the bench.

Tom Trbojevic (103) and Daly Cherry-Evans (93) both racked up plenty of points against the Bulldogs last week and could do similar things against North Queensland. Trbojevic proved to be great captaincy alternative to Cleary for those who took the gamble – will lightning strike twice?

Rabbitohs: Latrell Mitchell and Liam Knight are suspended, Adam Reynolds has a knee injury and Damien Cook, Cameron Murray, Cody Walker and Dane Gagai are among those being rested in a very new-look Souths line-up.

Blake Taaffe is at fullback, Taane Milne and Braidon Burns join the backline and Benji Marshall and Lachlan Ilias are the halves. Patrick Mago, Peter Mamouzelos and Jacob Host join the starting pack, and Dean Hawkins, Tautau Moga, Jed Cartwright and Davvy Moale form an entirely new bench.

Dragons: Zac Lomax (thumb) is out, with Gerard Beale at centre, while Poasa Faamausili replaces Jackson Ford on the bench.

Jack de Belin (51) and Jack Bird (47) were solid last week while Jayden Sullivan (70) has scored tries in back-to-bac games and Mikaele Ravalawa (80) has four tries in his past three games.

Titans: Moeaki Fotuaika starts with Sam McIntyre going to the bench, and David Fifita will again start on the interchange.

Fifita (73) had his best game in five weeks despite only playing 48 minutes off the bench against Newcastle, but is still too risky to be considered a captaincy option, while Jamal Fogarty (75) is still capable of a big score.

Warriors: Chanel Harris-Tavita returns in the halves for Chad Townsend (shoulder) and Jamayne Taunoa-Brown replaces Bunty Afoa on the bench, while Matt Lodge will challenge a potential ban at the judiciary on Tuesday night.

Addin Fonua-Blake (53) has become a pretty reliable scorer in the back half of the season, along with Euan Atiken (41), while Wayde Egan (74) had a line break, a try assist and four tackle breaks last week.

Wests Tigers: Kelma Tuilagi replaces Alex Seyfarth (knee) on the bench.

Forwards Stefano Utoikamanu (68), Alex Twal (60) and Luciano Leilua (54) were the Tigers' best last week, with Luke Brooks (32) sharing the general play kicking with base-price five-eighth Jock Madden (37).

Bulldogs: Matt Doorey (ACL) is out with Corey Waddell replacing him in the starting side.

He's gone under the radar a little this year but Josh Jackson (61) has been an incredibly consistent Fantasy scorer in the second half of the season, averaging 60 points a game since round 14 with no score below 50.

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